PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix
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چکیده
منابع مشابه
PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix
During embryonic development signalling pathways act repeatedly in different contexts to pattern the emerging germ layers. Understanding how these different responses are regulated is a central question for developmental biology. In this study, we used mouse embryonic stem cell (mESC) differentiation to uncover a new mechanism for PI3K signalling that is required for endoderm specification. We ...
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ژورنال
عنوان ژورنال: eLife
سال: 2013
ISSN: 2050-084X
DOI: 10.7554/elife.00806